HOPE
Studying the hippocampus from a developmental perspective
Reverse engineering the assembly of the hippocampal scaffold with novel optical and transgenic strategies
Features
Project duration
72 months
Start :
End :
Project scale
European project
Allocated budget
9 091 074,00 €
Description
The hippocampus is the part of the brain responsible for learning, emotions and memory formation. Emerging evidence suggests that development plays a key role in hippocampus function. HOPE is an EU-funded initiative that aims to investigate the neural circuits of the hippocampus and whether they are formed during development or are shaped by experience. The project will develop innovative methods that allow the tracing of genetically marked neuronal clones from birth into adulthood. In this way, HOPE will shed light on the emergence and plasticity of neural circuits in both physiological and pathological contexts.
Programme
ERC Synergy Grant
The aim is to provide support for a small group of two to four Principal Investigators to jointly address ambitious research problems that could not be addressed by the individual Principal Investigators and their teams working alone. Synergy projects should enable substantial advances at the frontiers of knowledge, stemming, for example, from the cross-fertilization of scientific fields, from new productive lines of enquiry, or new methods and techniques, including unconventional approaches and investigations at the interface between established disciplines. The transformative research funded by Synergy Grants should have the potential of becoming a benchmark on a global scale.
Project team
Partners
