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Published on : 15 May 2024

Postdoctoral position available in Autoimmune response in Retinal disease

Context

The Institut de la Vision is an international research center dedicated entirely to research into eye and vision diseases. It brings together researchers, doctors, patients and industry on the same site to discover innovative treatments for eye diseases and improve the quality of life of visually impaired people.

More than 300 researchers are working in the 5 research departments of the Institut de la Vision: developmental biology of the visual system, genetics, visual information processing, pathophysiology and therapeutics, photonics.

The research team

The team "Inflammation and Immunology in retinal diseases" studies the inflammatory mechanisms that lead to neuronal degeneration and vascular remodeling in age-related macular disease, diabetic retinopathy, and non-infectious uveitis.

https://www.institut-vision.org/en/research/inflammation-and-immunology-retinal-diseases

Missions

A two-year (one year renewable) postdoctoral position is available for a highly motivated PhD. The project will decipher the mechanisms involved in autoimmune response in a retinal pathology, Uveitis, with a focus on the role of purinergic receptors. In addition, the efficacy of a therapeutic approach using AAV vectors coding for specific nanobodies to modify the disease course will be evaluated in the mouse model of uveitis.

Position responsibilities include the use of different approaches to study immune responses in mouse models of retinal diseases established in the lab (Flow cytometry, RNAseq, scRNAseq, Histology). The successful candidate will be involved in study design, performing experiments, data collection, publishing results, and will present findings at seminars and conferences.

Skills required

Good writing and communication skills in English are expected as well as an ability to work in a team. 

Education and experience

Candidates with a PhD in Immunology, or Neuroimmunology during the past years and with experience in the fields of inflammation, autoimmunity, purinergic receptor, animal models, flow cytometry are encouraged to apply. Candidates whose expertise partly overlaps the requirements for this position are also welcome to apply, assuming there is interest in acquiring expertise with the other techniques.

How to apply

To apply for this vacancy, please complete this form and attach your cover letter and curriculum vitae in .pdf format. We will get back to you as soon as possible.

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One file only.
512 MB limit.
Allowed types: gif, jpg, jpeg, png, bmp, eps, tif, pict, psd, txt, rtf, html, odf, pdf, doc, docx, ppt, pptx, xls, xlsx, xml, avi, mov, mp3, mp4, ogg, wav, bz2, dmg, gz, jar, rar, sit, svg, tar, zip.