Electrophysiology engineer
Context
Our team's current research programme aims to study the cellular and molecular mechanisms involved in ocular pain, and more specifically corneal pain. Understanding the pathophysiology of this pain is essential for improving current treatments. Chronic ocular pain is one of the most incapacitating and difficult to treat conditions. This requires a deeper understanding of the anatomy of the corneal trigeminal nociceptive system (the cornea being the most innervated tissue in our body) and of the cellular and molecular mechanisms behind the onset and chronicisation of ocular pain. This particularly innovative research programme is structured around several areas in which the candidate will be involved.
We are looking for an electrophysiology engineer specialising in extracellular recording of corneal nerves to join our neuroscience research team. The successful candidate will be responsible for performing and analysing ex vivo extracellular electrophysiological recordings to study the electrical activities of corneal nerves in various experimental and pharmacological contexts related to dry eye.
The research team
Our team is the only team in France and one of the few in the world to develop translational studies dedicated to ocular pain. Innovative fundamental and clinical research projects, conducted in collaboration with the Clinical Investigation Center and the Ophthalmobiology Laboratory at the Quinze-Vingts Hospital, aim to deepen our understanding of peripheral and central mechanisms associated with chronic dry eye disease and pain.
Our objective is to discover promising new therapeutic approaches aimed at alleviating pain in patients who currently lack effective treatments.
https://www.institut-vision.org/en/research/pathophysiology-anterior-segment-eye
Missions
Electrophysiological recording :
Perform ex vivo extracellular electrophysiological recordings of corneal nerves.
Use specialised software to process and analyse electrophysiological data (e.g. Spike 2).
Design and implementation of experiments :
Designing experimental protocols for studying the electrophysiological activities of the corneal nerves in an ex vivo model.
Working with the various members of the research team to plan and carry out experiments.
Writing Scientific Protocols and Reports:
Documenting experimental protocols and formatting the results obtained.
Writing scientific reports and publications.
Equipment maintenance:
Operating and maintaining electrophysiology equipment, in particular amplifiers and data recording systems.
Skills required
- Certification in animal experimentation at applicator or designer level
Interpersonal skills:
- Written and oral communication skills for writing reports and presenting scientific results.
- Ability to work as part of a team and to collaborate with different team members.
Personal skills:
- Scientific rigour.
- Good interpersonal skills and sense of teamwork
- Availability and responsiveness
- Spirit of initiative.
Education and experience
Education :
- Engineering degree or Master's degree in neuroscience.
- Certification in animal experimentation at applicator or designer level.
Experience required:
- Experience in designing and implementing experimental protocols for recording and analysing electrophysiological signals.
- Proficiency in electrophysiology techniques for extracellular recording.
- Proficiency in electrophysiological data processing software (e.g. Spike 2).
How to apply
To apply for this vacancy, please complete this form and attach your cover letter and curriculum vitae in .pdf format. We will get back to you as soon as possible.